Immune Modulatory Effects of Vitamin D on Viral Infections
Nutrients 2020, 12(9), 2879; https://doi.org/10.3390/nu12092879
by Maheen Siddiqui 1,†,Judhell S. Manansala 1,†,Hana A. Abdulrahman 2,Gheyath K.
Nasrallah 1,2OrcID,Maria K. Smatti 2OrcID,Nadin Younes 1,2,Asmaa A. Althani 1,2 andHadi M. Yassine 1,2,*OrcID
1 College of Health Science-QU Health, Qatar University, Doha 2713, Qatar
2 Biomedical Research Center, Qatar University, Doha 2713, Qatar
- Overview HIV and vitamin D
- Colds and flu prevented and treated by Vitamin D - many studies
- Respiratory infections reduced by 63 percent with 4000 IU vitamin D daily - RCT Dec 2012
- Hepatitis B virus and Vitamin D - many studies
- Vitamin D prevents Hepatitis-C and helps treat it (many studies)
- Overview Influenza and vitamin D
Virus category starts with the following
see also
Immunity, Ebola, HIV, Influenza Hepatitis B Hepatitis-C,Rotavirus, Shingles Enveloped Virus Virus-Pregnancy category has
Many viruses can apparently be dealt with by:
- Vaccination (if avaiable & affordable and person is willing to have the side-effects - which can include death)
- Getting Vitamin D into your blood
- Increasing the vitamin D actually getting to cells Magnesium, Omega-3, Resveratrol, etc
Especially enveloped viruses", Herpes, Zoster, Epstein, Hepatitis, Ebola, Dengue, Yellow fever, Measles, Mumps, smallpox
COVID-19 treated by Vitamin D - studies, reports, videos as of Sept 17 included
- 32 trial registrations, 1 trial result, 19 observations, 9 recommendations, 42 associations, 68 speculations, 23 videos
- and now has the following recent updates
Top Vitamin D and COVID-19 recent updates
- COVID-19 defeated 3x faster by 420,000 IU Vitamin D nanoemulsion – RCT Nov 12, 2020
- 2X fewer COVID-19 deaths observed if infrequent vitamin D (2X more deaths if daily dose) – UK Oct 20, 2020
- Vitamin D fighting COVID-19 meets Bradford Hill Criteria - Nov 2020
- French National Academy recommended 100,000 IU of Vitamin D to elderly to fight COVID-19 - May 2020
- Chinese COVID-19 study – 80 pct of severe cases had low Vitamin D, all asymptomatic cases had OK Vit D – Oct 13, 2020
- Vitamin D and COVID-19 - observational studies found it helps, never hurts - Campbell Oct 31, 2020
- COVID-19 increased risks with low vitamin D: Infection 1.5 X, Hospitalization 1.8 X – meta-analysis Oct 2020
- COVID-19 lung death 4X more likely in Iran if less than 25 ng of vitamin D – Oct 30, 2020
- Evidence Regarding Vitamin D and Risk of COVID-19 and its Severity - Oct 27, 2020
- COVID-19 patients who happened to be taking Vitamin D did much better – Oct 27,2020
- 9X COVID-19 survival in nursing home if had 80,000 IU dose of vitamin D in previous month – Oct 2020
- COVID-19 fought by Vitamin D in 43 studies - Oct 15, 2020
- 15 studies indicating that Vitamin D fights COVID-19 - Dr. Grimes Oct 9, 2020
- 32X more likely to have severe-critical COVID-19 in Turkish hospital if Vitamin D deficient – Oct 5, 2020
- Vitamin D Cuts SARS-CoV-2 Infection Rate by Half Mercola Sept 28
- 47% lower SARS-CoV-2 positivity rate if > 50 ng vs < 20 ng
- 58% lower risk of testing positive for SARS-CoV-2 if > 30 ng vs < 30 ng
- 2X higher risk of hospitialization if <30 ng
- ICU patients got semi-activated Vitamin D - death rate dropped to 2% from 50%
- Virtually no COVID-19 cases in countries having more than 30 ng of Vitamin D - Sept 17, 2020
- Studies on Vitamin D and COVID-19 (11 categories) - Sept 20, 2020
- Rate of COVID-19 test positive is 40 pcnt lower if high vitamin D (192,000 people) - Holick Sept 2020
- 14.7 X more likely to die of COVID-19 if less than 12 ng of Vitamin D (185 Germans) – Sept 10, 2020
- Low D increases risk of infection. Dr. Fauci Sept 11
- "If you're deficient in vitamin D, that does have an impact on your susceptibility to infection. I would not mind recommending, and I do it myself, taking vitamin D supplements,..." 32 minutes into Instagram interview
- Dr. Fauci takes 6,000 IU of Vitamin D daily – Sept 2020
Click on chart for details
- COVID-19 defeated by activated Vitamin D in Spain - pilot RCT Aug 29, 2020
- WHO – Severe COVID-19 mortality reduced by hormones (should consider hormone D too) - Sept 2020
- Vitamin D in Prevention and Treatment of COVID-19 (16 reasons) – Sept 1, 2020
Search Google Scholar for COVID-19 Vitamin D 20,000 publications Oct 10, 2020
 Download the PDF from Vitamin D Life
Viral infections have been a cause of mortality for several centuries and continue to endanger the lives of many, specifically of the younger population. Vitamin D has long been recognized as a crucial element to the skeletal system in the human body. Recent evidence has indicated that vitamin D also plays an essential role in the immune response against viral infections and suggested that vitamin D deficiency increases susceptibility to viral infections as well as the risk of recurrent infections.
For instance, low serum vitamin D levels were linked to increased occurrence of high burdens viral diseases such as hepatitis, influenza, Covid-19, and AIDS. As immune cells in infected patients are responsive to the ameliorative effects of vitamin D, the beneficial effects of supplementing vitamin D-deficient individuals with an infectious disease may extend beyond the impact on bone and calcium homeostasis. Even though numerous studies have highlighted the effect of vitamin D on the immune cells, vitamin D’s antiviral mechanism has not been fully established. This paper reviews the recent mechanisms by which vitamin D regulates the immune system, both innate and adaptive systems, and reflects on the link between serum vitamin D levels and viral infections.
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