Is There Any Relationship between Vitamin D Deficiency and Gross Motor Development in 12-Month-Old Children?
Iran J Child Neurol. 2019 Summer;13(3):55-60. PMID: 31327969
Tavakolizadeh R1, Ardalani M1, Shariatpanahi G1, Mojtahedi SY1, Sayarifard A2.
1 Ziaeeyan Hospital, Tehran University of Medical Sciences, Tehran, Iran.
2 Growth and Development Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Poor motor development in infant was 40 percent more likely if low maternal vitamin D – July 2017
2X improved development by severely malnourished children with 2 loading doses of vitamin D – RCT May 2018
- Children 3X less likely to have delayed gross motor dev. if given 2 doses of 200,000 IU 8 weeks before
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Impact of Vitamin D Supplementation on Gross Motor Development of Healthy Term Infants: A Randomized Dose-Response Trial
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We aimed to assess the possible relationship between vitamin D deficiency and gross motor developmental milestones in Iranian children in Tehran City, Iran.
MATERIALS & METHODS:
In this cross-sectional study, 186 healthy children of one-yr-old age referring to a children hospital in Tehran, Iran from May 2015 to April 2016, were enrolled. The gross motor developmental milestone of children and their serum vitamin D concentration were evaluated.
RESULTS:
Overall, 186 children, 92 males (49.5%) were studied. Twenty-four patients (12.9%) just were able to sit without support, and 40 patients (21.5%) to stand alone and to sit without support. Besides, 122 patients (65.6%) were able to walk with assistant or alone and to sit without support and stand alone. Vitamin D was sufficient in 148 children (79.6%), insufficient in 32 (17.2%) and deficient in 6 (3.2%). Sufficient vitamin D was significantly correlated with walking ability (P<0.001, OR=3.9, 95%CI=1.9-8.4).
CONCLUSION:
Considering the significant correlation between vitamin D deficiency and gross motor developmental milestones in this population of children, children referring to gross motor developmental delay need to be thoroughly evaluated for vitamin D deficiency.