50,000 IU of Vitamin D once every two weeks proven to prevent/treat:
Diabetes + Heart Failure + Chronic Pain + Depression + Autism + Breast Cancer + Colon Cancer + Prostate Cancer + Preeclampsia + Premature Birth + Falls + Cognitive Decline + Respiratory Tract Infection + Influenza + Tuberculosis + Chronic Obstructive Pulmonary Disease + Lupus + Inflammatory Bowel Syndrome + Urinary Tract Infection + Poor Sleep + Weight Loss + Growing Pain + Multiple Sclerosis + PMS + Schizophrenia (25 problems)
See down this page: Additional health problems fought by 50,000 Vitamin D WEEKLY
17 additional, for a total of 42 health problems fought if take 50,000 IU weekly
- Diabetes helped by daily 4,000 IU of Vitamin D – meta-analysis Sept 2017
- which is very close to 50,000 IU every two weeks
- Diabetes treated if given enough vitamin D (example: 50,000 IU weekly) – review of RCT - Jan 2017
- Gestational Diabetes reduced with 50,000 IU of vitamin D every 3 weeks and daily Calcium – RCT June 2014
- Prediabetes reduced by monthly 60,000 IU of vitamin D – RCT May 2015
- Diabetics are 2.7 X more likely to get peripheral neuropathy if low vitamin D – meta-analysis Dec 2014
- Type 2 diabetes 1.5X more likely if low vs high vitamin D – meta-analysis Feb 2013
- Type 1 Diabetes (T1DM) 1.6 X more likely if low vitamin D – meta-analysis Jan 2018
- Diabetes (Type 1) 14X more likely in dark skin children with low levels of vitamin D – May 2015
- Many Diabetics guts poorly absorb standard vitamin D - need injection of gut-friendly form
- Diabetics were 4.4 X more likely to die if they had low Vitamin D – July 2018
- Diabetics helped by vitamin D in 5 ways – meta-analysis June 2018
- Stroke or coronary heart disease deaths 30% less likely if had taken more than 440 IU of vitamin D (900,000 patient years) – Jan 2018
- Cardiovascular deaths 12 percent less likely if have 10 ng more vitamin D – meta-analysis March 2017
- Chronic Heart Failure improved with 4,000 IU daily for a year – RCT April 2016
- Seniors with Heart Failure helped by daily 4,000 IU of vitamin D (increase 16 ng) – RCT Aug 2014
- Congestive heart failure in infants virtually cured by 1000 IU of vitamin D – RCT Feb 2012
- Acute Heart Failure length of stay and readmission rates cut in half if high vitamin D – Aug 2017
- 7X increased chance of death if coronary artery disease and low vitamin D – Oct 2013
- Chronic Pain reported 38 percent less often if supplemented with Vitamin D – meta-analysis Sept 2016
- Note - many studies found a variety of types pain were prevented or relieved by weekly 50,000 IU
- Shin pain in elderly men 36 X more likely if low vitamin D – March 2017
- Back and leg pain lasts a year longer if low vitamin D – April 2017
- Fibromyalgia treated with Vitamin D (50,000 IU weekly for 3 months) – 2016, 2017, 2018, 2019
Depression
- Anti-depression medication about as good as big increase in vitamin D – meta-analysis of flawless data April 2014
- Depression in adolescent girls reduced somewhat by 50,000 IU weekly for 9 weeks – July 2017
- Vitamin D depression RCT canceled: too many were taking Vitamin D supplements, etc. Feb 2018
Autism
- Autism treated by Vitamin D (80 – 120 ng) – Cannell update May 2018
- Autism risk factors – many are associated with low vitamin D – meta-meta-analysis March 2017
- Vitamin D and autism - treat: 300 IU per kg per day, prevent: during pregnancy 5,000 IU – Feb 2017
- Autistic children were 3.6 X more likely to have low levels of vitamin D – Nov 2017
Breast cancer
- Breast Cancer 80 percent less likely if high level of vitamin D – June 2018
- Breast Cancer prevented by Vitamin D (most studies concur) – Dec 2017
- Breast cancer 60% reduction with 1100 IU of Vitamin D - RCT
- Breast Cancer Mortality reduced 60 percent if more than 60 ng of Vitamin D – meta-analysis June 2017
- 17 meta-analyses of Breast Cancer as of Sept 2017
Colon Cancer
- Colorectal cancer is associated with Vitamin D (17 meta-analyses so far) – July 2018
- Colorectal cancer 60 percent less likely if have more than 50 ng of vitamin D (vs 5 ng) – meta-analysis April 2017
- Colon cancer – how vitamin D prevents and treats it – Nov 2014
- 45 percent fewer deaths from digestive cancers for 10 ng increase in vitamin D – 2006
Prostate Cancer
- Prostate cancer risk increase with Vitamin D (other studies disagree) – meta-analysis Jan 2018
- Prostate cancer reduced when 4000 IU vitamin D was added– Hollis RCT April 2015
- Prostate cancer in veterans more survivable when have enough vitamin D – Jan 2014
- 7X increase in stage IV Prostate Cancer survival when vitamin D greater than 32 ng – May 2013
Preeclampsia
- Preeclampsia recurrence reduced 2 X by 50,000 IU of vitamin D every two weeks – RCT July 2017
- Preeclampsia reduced by Vitamin D (50,000 IU bi-weekly) and Calcium – Oct 2015
- Preeclampsia rate cut in half by high level of vitamin D – meta-analysis March 2014
- Preeclampsia 2.7X more frequent if low vitamin D – meta-analysis Sept 2013
Premature Birth
- Vitamin D intervention reduces preterm births and low birth weight by 60 percent – Cochrane Reviews – Nov 2017
- Preterm birth rate reduced 57 percent by Vitamin D – Nov 2015 4,000 IU?
- Preterm birth rate reduced by 43 percent with adequate Vitamin D supplementation – meta-analysis Feb 2017
Falls
- Falls cut in half by 100,000 IU vitamin D monthly - RCT 2016
- Elderly falls reduced 3.6 times by 900 IU of vitamin D and simple exercise – RCT Nov 2016
- 39% fewer falls with 2000 IU than 800 IU – RCT June 2010
- Hip fracture 58 percent more likely if low vitamin D – meta-analysis March 2017
- Free Vitamin D in New Zealand to prevent falls in nursing homes (50,000 IU monthly) – June 2016
Cognitive Decline
- Cognition of Alzheimer’s patients improved by daily 4,000 IU of vitamin D – RCT Jan 2015
- 2,000 IU of vitamin D reduced schizophrenia chance by 77 percent (male infants) - 2004
- Severe Alzheimer's delayed by 1 year with vitamin D intervention – March 2014
- Mental health intervention trials using enough vitamin D for long enough found benefits – Jan 2017
Respiratory Tract Infection
- Respiratory Tract visits 2.5 less likely with vitamin D: Pregnancy 2000 IU, Infant 800 IU – RCT Oct 2014
- Respiratory infections cut in half by 20,000 IU weekly vitamin D if initially deficient – RCT March 2015
- Respiratory tract infection eliminated in 36 percent of people by 4000 IU of Vitamin D – RCT Sept 2015
- Acute respiratory tract infections prevented by vitamin D (even when ignoring the dose size – Meta-analysis Feb 2017
- Vitamin D reduces respiratory tract infections by 40 percent– meta-analysis Dec 2012
- Reduced viral respiratory tract infections by half by having more than 38 ng of vitamin D – June 2010 many people get > 38 ng with 50,000 every two weeks
Influenza
- Influenza prevented by 40 ng levels or treated with vitamin D hammer (50,000 IU) – June 2015 a single 50,000 IU dose
- Half the risk of Influenza -A in infants taking 1200 IU of vitamin D for 4 months – RCT Jan 2018
- Overview Influenza and vitamin D
Tuberculosis
- Tuberculosis 4.5X more likely if vitamin D less than 10 nanogram – meta-analysis May 2015
- Probability of getting TB reduced 60 percent with just 800 IU of vitamin D – RCT Aug 2012
- Tuberculosis risk decreased by 6 percent for each 1 ng increase in Vitamin D – Oct 2014
- Tuberculosis -100 percent cure rate with 10,000 IU of vitamin D daily – RCT 2006 which is about 50,000 every week
- Tuberculosis recovery speeded up by single 450,000 IU dose of vitamin D – RCT Jan 2017
Chronic Obstructive Pulmonary Disease
- COPD reduced by 40 percent with monthly 100,000 IU of vitamin D – RCT Jan 2015
- 100000 IU vitamin D monthly helps COPD patients – 3 RCT
Lupus
- Lupus flareups cut in half by just 2,000 IU of vitamin D – RCT Dec 2012
- Lupus flares totally eliminated by loading dose then 100000 IU of vitamin D each month – Oct 2012
- Musculoskeletal pain reduced with 4,000 IU of vitamin D – RCT April 2015 Lupus pain
- Lupus helped by Vitamin D supplementation in 3 out of 4 studies – Oct 2017
- Lupus is both prevented and treated by Vitamin D – review Dec 2017
Inflammatory Bowel Syndrome
Urinary Tract Infection
- UTI associated with low Vitamin D, treated by Vit. D, many UTI now resistant to antibiotics 50,000 IU every 2 weeks should be very similar
- Urinary Tract Infection in infants 5.6 X MORE likely if low Vitamin D, 3.3 X LESS likely if supplement – July 2016
Multiple Sclerosis
PMS
Schizophrenia
Note - Magnesium and Omega-3 supplementation often provide similar benefits for the above health problems
Taking one 50,000 IU capsule of Vitamin D3 every two weeks will result in 80% of adults bringing their blood levels to above 40 nanograms/ milliliter in 2-6 months, an optimal level for good health.
You can take 50,000 IU pills daily in the first week and feel the benefits by the end of the week
Feeling the benefits quickly greatly increases the likelyhood that you will continue with supplementation
50,000 IU | To feel benefits in a week | To maintain >40 ng/ml for 80% of people |
Adult | 1 per day | 1 every 2 W |
Adult - high risk* | 2 per day | 1 every week |
A 50,000 IU capsule costs as little as 20 cents, ($20 retail for a bottle of 100 capsules Amazon US )
The very lowest cost source and highest quality of vitamin D3 50,000 IU capsule = Bio-Tech
You can order it from Amazon US (Amazon has the lowest price, but has a policy to not ship any health care products out of a country)
*UK company that ships Bio-Tech products to all the European countries
WLS sells Bio-Tech from the Netherlands to Europe
Many companies on Amazon supply Vitamin D - Sept 2017
Dose size | Suppliers | |
50,000 IU | 8+ | |
10,000 IU | 30+ | |
5,000 IU | 500+ | |
4,000 IU Upper limit specified by IoM | 20+ |
An adult who is not at high risk for vitamin D deficiency can achieve an optimal level with just 8 capsules of 50,000 IU
If at high risk: at least double the number of capsules will be needed for loading and maintenance
Bio-Tech Pharmacal
Status March 28, 2020 - they have stock of the D3-50,000 textVegicap
Bio-Tech makes the only Vitamin D which has ALL of these features:
Very low cost | 50,000 IU capsule appears to be the lowest cost source in the world | |
Contains no additives | Nothing to cause an allergy | |
Does not have oil base | Oil is associated with about 20% reduction in response in a clinical trial water-soluble is far more absorbable | |
Tasteless | No unpleasant taste or odor as with some liquids | |
Tiny capsule need not be swallowed | You can put the capsule powder into water, milk (animal or plant), juice, food, etc and consume your vitamin D over the period of days. | |
Kosher and Halal certified | Vegi-cap (needed for Kosher) is more expensive | |
Gut friendly | Though some companies have even gut friendlier forms |
Opinion: Founder of Vitamin D Life
> 95% of people will get full benefit from Bio-Tech Vitamin D
~50% of people will get full benefit from most of the other brands of vitamin D
due to poor gut, allergies, unable to take pills, etc,
Alternately: take 4,000 IU daily (instead of 50,000 bi-weekly
cost is 4X higher, and have 13 more opportunities to forget
Note: Institute of Medicine says upper limit is 4,000 IU (average per day)
4,000 IU | To feel benefits in a week | To maintain >40 ng/ml 80% of people |
Adult | 20 per day for 4 days | 1 per day |
Adult - high risk* | 40 per day for 4 days | 2 per day |
Child | 10 per day for 4 days | every other day |
Additional companies which ship internationally include (Note: customs rarely seem concerned about dose size if small quantities, especially via mail)
Swansons, Life Extension Foundation Vitaminshoppe Nutrition Express - can sort by size or type Ebay 10,000 listings in Nov 2016
Cofactors should be adjusted- especially if take for many months
Reduce Calcium intake to 500 mg/day (dairy products, food, supplements)
Increase Magnesium supplements to 500 mg/day
Additional Vitamin D references
Every 2 weeks 50,000 IU
- Treating Vitamin D deficiency in senior women – such as 50,000 IU daily for 15 days then twice a month – Review April 2019
- 50,000 IU of vitamin D every two weeks – Jordan conclusion - RCT July 2017
- Vitamin D update – 40-60 ng ideal, 50K biweekly maintenance – Jan 2014
- Insulin resistance during pregnancy improved with 50,000 IU of vitamin D every 2 weeks – RCT April 2013
- Even taking as much as 4200 IU vitamin D 43 percent had less than 30 ng in blood – RCT Jan 2013 need more?
- Monthly vitamin D dosing is better than daily dosing for children and elderly (more likely to be taken) – June 2017
- Vitamin D RCT using 100,000 IU monthly for a variety of health problems – results of ViDA due in 2016
What is an Optimal Level: 40 ng, 50 ng, 60 ng, 80 ng?
- Is 50 ng of vitamin D too high, just right, or not enough
- Optimum Vitamin D level: Evidence for 30 and 40 ng – Grant Aug 2013
- 30 to 50 ng of vitamin D is optimal – Central Europe consensus Sept 2013
- Defining normal level of vitamin D (need 4000-5000 IU) - Heaney Spring 2013
- 40 ng Vitamin D perhaps optimal for reduced mortality – Meta-analysis Jan 2012
- Fewer health problems with higher Vitamin D Levels has the following chart
Loading doses of Vitamin D
High Risk of being having low vitamin D levels
- Obese, Seniors, Pregnant, Shut-in, Dark Skin, very far from equator, recent surgery/major medical
avoid the sun, excessive clothing, gut problems, kidney/liver problems, etc. - High Risk of little Vitamin D category overview with associated searches
- Obese need 2.5 IU of vitamin D per kg to increase 1 ng (about 3.4 X more) – RCT Sept 2013 example of a high-risk group
- 50,000 IU vitamin D weekly increased levels by 52 ng normally, but only 28 ng if obese – Oct 2013
Extremely low Toxicity Note: 50,000 IU is not even toxic if taken daily for 30 days
- Millions of people have taken single dose of 500,000 IU of vitamin D without any problem
- 10,000 IU daily can be taken for years and years. (The body naturally removes any excess)
- Overview Toxicity of vitamin D
- Some indication that too much vitamin D causes problems in hospitals
- 100,000 IU monthly vs placebo RCT Aug 2018
adverse events in 16% of both Vitamin D and placebo groups: 10.1016/j.clnu.2018.07.034
Use the same 50,000 IU pill monthly for chilgren
Other Vitamin D information
- Does Less Sun mean More Disease video tells you WHY vitamin D is needed
- Overview Deficiency of vitamin D
- 79+ Randomized Clinical Trials with non-daily dosing
Note: very little difference if Vitamin D is taken every day or with 16 X a dose taken every 16 days - Vitamin D deficiency is a major global public health problem – Maps Nov 2013
- Would you be opposed to my getting more vitamin D
- How to ask your doctor if you should take more vitamin D
- Overview Rare Allergic reaction to vitamin D
- Magnesium, wool, oil, etc. About 1 in 300 people, typically due to low level of Magnesium
- Vitamin D3 for Vegans Vegan D3 surprisingly does not cost much more
- Low Cost vitamin D - including liquid and bulk typically 5 cents per 5000 IU
- Overviews at Vitamin D Life
- Proof that Vitamin D Works 87 proofs as of Aug 2018
- Even taking as much as 4200 IU vitamin D 43 percent had less than 30 ng in blood – RCT Jan 2013
- 30 percent of vitamin D sold now has more than 2000 IU - Dec 2012 vs US govt says 600 IU is enough
- How you might double your response to vitamin D
- 85% achieved 20 ng with avg of 3300 IU of vitamin D - oral and injection Aug 2012
- Breastfeeding with daily or monthly doses of vitamin D virtually the same – RCT Dec 2013
- It is OK to miss getting your vitamin D supplement by even a week - just take it when you remember to do so.
- If you have gut problems or poor absorption, you should probably take Vitamin D3 in a more easily absorbable form such as BioMulsion gel
- Alternatives if not swallow pills or not absorb vitamin D
- If you just have a maintenance dosing without loading dose it will take 6-9 months to feel the benefits
- No need to test your vitamin D blood level - But, a test will confirm when you are getting enough Vitamin D
- Many different forms are available
- Oil-based Vitamin D3 has the worst bioavailability – April 2014
- There are many near-term benefits to be felt by having an optimum level of vitamin D
- There is a 4X variability in response between individuals
The dose sizes on this page may be two times higher or 2 times lower than what you need - About 5% of the population should not supplement with vitamin D
generally because Vitamin D increases or decreases the affect of their medications ( Contra-indications )
When in a hospital, you must make them aware that you have a higher level of vitamin D than most of the population Virtually all drug doses assume low levels of vitamin D, and high levels can increase/decrease potency by 3X. A Chemo dose, for example, might be decreased by 3X for people with optimal vitamin D, giving you much less trauma, but if not reduced you might die.
Review of vitamin D interaction with drugs – Jan 2014 - Let your calendar remind you when to take your supplement - Not have to remember: Which SUNday is this?
- Healthy in Seven Days - Loading dose of Vitamin D – book 2014
Restocking vitamin D quickly gets you to a good level in less than a week instead of less than a year - Vitamin D once every two weeks is OK, daily is nice but not required – Aug 2014
- Breastfeeding with daily or monthly doses of vitamin D virtually the same – RCT Dec 2013
17 additional Health Problems fought when taking 50,000 IU Vitamin D weekly
See also
short URL = https://is.gd/VitD2weeks