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Vitamin D receptor (TT), which restricts Vit D to cells, is associated with balance problems in seniors – June 2018

Postural Balance and Vitamin D Receptor Gene Polymorphism in Physically Independent Older Adults

International Conference on Applied Human Factors and Ergonomics. AHFE 2018:
Advances in Human Factors and Ergonomics in Healthcare and Medical Devices pp 397-404 |
https://doi.org/10.1007/978-3-319-94373-2_44
Regina Poli-Frederico Marcos Fernandes Rubens A. da Silva Karen Fernandes

Vitamin D Life

G1 (44% ) = TT genotype group = poorer balance
G2 (56%) = TC or CC genotypes = better balance

Balance Test
Image

Need more balance area (Center of Pressure)
for 1-legged stand: 14 vs 10

Image

Sway more if TT VDR
Image


Note: Falls are associated with low Vitamin D blood levels
The VDR (TT) restricts how of it actually gets to the cells

Falls and Fractures category contains the following summary

Hip fracture

Vitamin D Receptor category has the following

384 studies in Vitamin D Receptor category

Vitamin D tests cannot detect Vitamin D Receptor (VDR) problems
A poor VDR restricts Vitamin D from getting in the cells
It appears that 30% of the population have a poor VDR (40% of the Obese )

A poor VDR increases the risk of 55 health problems  click here for details
The risk of 44 diseases at least double with poor Vitamin D Receptor as of Oct 2019

VDR at-home test $29 - results not easily understood in 2016
There are hints that you may have inherited a poor VDR

Compensate for poor VDR by increasing one or more:

IncreasingIncreases
1) Vitamin D supplement
  Sun, Ultraviolet -B
Vitamin D in the blood
and thus in the cells
2) MagnesiumVitamin D in the blood
 AND in the cells
3) Omega-3 Vitamin D in the cells
4) Resveratrol Vitamin D Receptor
5) Intense exercise Vitamin D Receptor
6) Get prescription for VDR activator
   paricalcitol, maxacalcitol?
Vitamin D Receptor
7) Quercetin (flavonoid) Vitamin D Receptor
8) Zinc is in the VDRVitamin D Receptor
9) BoronVitamin D Receptor ?,
etc
10) Essential oils e.g. ginger, curcuminVitamin D Receptor
11) ProgesteroneVitamin D Receptor
12) Infrequent high concentration Vitamin D
Increases the concentration gradient
Vitamin D in the cells
13) Sulfroaphone and perhaps sulfurVitamin D Receptor

Note: If you are not feeling enough benefit from Vitamin D, you might try increasing VDR activation. You might feel the benefit within days of adding one or more of the above

Far healthier and stronger at age 72 due to supplements Includes 6 supplements which help the VDR

PDF is available free at Sci-Hub   10.1007/978-3-319-94373-2_44
This study aimed to assess the association between VDR polymorphisms and postural balance in physically independent elderly. 142 elderly persons were enrolled at this case-control study. In order to assess the balance, the individuals performed three 30-s trials of one-legged stance balance test on a BIOMEC400 force-platform (EMG System of Brazil, SP Ltda.), following a standardized protocol (with 30 s of rest between each trial). The main balance parameters used for analysis were: center of pressure area (COP), sway velocity (cm/s) and frequency (s) in both the antero-posterior (A/P) and the medio-lateral (M/L) axes. The VDR TaqI polymorphism analysis was by PCR-RFLP. The case group showed lower values of COP, sway velocity in A/P and M/L axes (p = 0.0007). Similar data were observed regarding frequency in A/P (p = 0.04) and M/L axes (p = 0.03). Therefore, carriers of the “C” allele have a better postural balance when compared to individuals with “T” allele.

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Created by admin. Last Modification: Monday July 2, 2018 21:52:05 GMT-0000 by admin. (Version 7)

Attached files

ID Name Comment Uploaded Size Downloads
10068 Sway.jpg admin 01 Jul, 2018 18:04 8.92 Kb 372
10067 Center of Pressure.jpg admin 01 Jul, 2018 18:04 10.42 Kb 391
10066 Balance test.jpg admin 01 Jul, 2018 18:04 15.65 Kb 380
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