54,000 IU of vitamin D daily with no Calcium (1,000 IU per kg: Coimbra protocol)

Resolution of Optic Neuritis and Probable Multiple Sclerosis after Long-Term Ingestion of Very High Doses of Vitamin D3: A Case Report

Neuroimmunology Reports, https://doi.org/10.1016/j.nerep.2024.100224

Nipith Charoenngam 1 2, Michael F. Holick 1

PTH bottomed-out (as expected) in a few months

A 36-year-old male presented with 2 months of left-eye visual disturbance and was diagnosed with optic neuritis due to probable multiple sclerosis (MS). He was advised to undergo periodic ophthalmology follow-up without immunosuppressive treatment. Due to persistent symptoms, he expressed interest in very high-dose vitamin D3 therapy of 54,000 IUs/day (1,000 IUs/kg/day) along with a zero-calcium diet. After starting the therapy, he experienced sustained symptomatic improvement of visual symptoms over 4 years, along with radiological stability of the optic neuritis lesion without developing hypercalcemia. This case supports the potential therapeutic efficacy of very high-dose vitamin D for MS.

📄 Download the PDF from Vitamin D Life

Vitamin D Life - Coimbra high-dose vitamin D protocol - many studies

Note: Coimbra protocol consists of much more than just high vitamin D and no Calcium

Vitamin D Life – Multiple Sclerosis and (lots of) Vitamin D - book by patient on Coimbra protocol - Feb 2016 contains protocol description__

{include}

MS updates from Brazil

{include}

Vitamin D Life – Overview MS and vitamin D contains

{include}

Vitamin D Life - Response to Vitamin D - many studies

Vitamin D Life – Comparing High-dose vitamin D therapies contains:

{include}