Autism treated by an activator of the Vitamin D Receptor: supforaphane
New Study Shows Promise for Natural Support of Autism Symptoms - March 2024
"A new double-blind, placebo-controlled study published in Psychiatry and Clinical Neurosciences shows exciting potential for sulforaphane, a compound found in broccoli sprouts, to help ease symptoms of irritability and hyperactivity in children with autism spectrum disorder (ASD)."
- "After 10 weeks, the sulforaphane group showed significantly greater improvements in irritability scores and hyperactivity/noncompliance scores compared to placebo. However, no differences were seen between groups in other symptom areas like lethargy, stereotypic behavior, or inappropriate speech."
" A study published in Psychiatry and Clinical Neurosciences found that when used as an adjunctive treatment alongside risperidone , sulforaphane significantly improved symptoms of irritability and hyperactivity in children with ASD compared to placebo."
"Early studies associate sulforaphane with reduced risks for cardiovascular disease, asthma, schizophrenia, Alzheimer's disease, and Parkinson's disease.8 It has been shown to support liver function, blood sugar balance, eye health, skin reactions, detoxification and even slowing the aging process itself. With over 250 recorded health benefits, sulforaphane's therapeutic potential appears tremendous.9"
Momtazmanesh, S., Amirimoghaddam-Yazdi, Z., Moghaddam, H.S., Mohammadi, M.R. and Akhondzadeh, S., 2020. Sulforaphane as an adjunctive treatment for irritability in children with autism spectrum disorder: A randomized, double-blind, placebo-controlled clinical trial. Psychiatry and Clinical Neurosciences, 74(7), pp.398-405.
Note: there appears to be no mention in the article that sulforaphane is a VDR activator
Study had been cited 40 times as of Dec 2024
- Efficacy of Sulforaphane in Treatment of Children with Autism Spectrum Disorder: A Randomized Double-Blind Placebo-Controlled Multi-center Trial - Feb 2024 https://doi.org/10.1007/s10803-022-05784-9
- ". There were no significant changes in caregiver rated scales between sulforaphane and placebo groups. However, clinician rated scales showed a significant improvement in the sulforaphane group, and one third of participants showed at least a 30% decrease in score by 12 weeks treatment."
Vitamin D Life - Activators of the Vitamin D Receptor include sulforaphane and curcumin – June 2020
Vitamin D Life - studies in both categories Autism and Vitamin D Receptor
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Vitamin D Life – Autism category contains:
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Vitamin D Life - The risk of 50+ diseases at least double with poor Vitamin D Receptor
Vitamin D Life - Vitamin D Receptor activation can be increased in many ways
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Vitamin D Life – The Vitamin D Receptor is associated with many health problems
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