Causes, consequences, and treatment of osteoporosis in men

Drug Des Devel Ther. 2013 Aug 22;7:849-860.

Banu J.

Coordinated Program in Dietetics, College of Health Sciences and Human Services and Department of Biology, College of Science and Mathematics, University of Texas-Pan American, Edinburg, TX, USA.

Men undergo gradual bone loss with aging, resulting in fragile bones. It is estimated that one in five men will suffer an osteoporotic fracture during their lifetime.

The prognosis for men after a hip fracture is very grim.

A major cause is reduction of free testosterone.

Many other factors result in secondary osteoporosis, including treatment for other diseases such as cancer and diabetes.

Patients should be screened not only for bone density but also assessed for their nutritional status, physical activity, and drug intake.

Therapy should be chosen based on the type of osteoporosis.

Available therapies include

• testosterone replacement,

• bisphosphonates, and

• nutritional supplementation with calcium, vitamin D, fatty acids, and isoflavones, as well as

• certain specific antibodies, like denosumab and odanacatib, and inhibitors of certain proteins.

PMID: 24009413

Notes

1. Fails to deal with prevention: vitamin D, Vitamin K, Magnesium, Boron, decreased Vitamin A, DECREASED Calcium

2. Discusses bone mass, when what is important is bone strength

   • Just adding bone mass will typicall add thickness, but not bone strength (does not re-create the structure)

PDF is attached at the bottom of this page

See also Vitamin D Life

• Overview Osteoporosis and vitamin D

• Osteoporosis: Diagnosis and Management (professional book) – Oct 2013

• 22 percent more bone cracking found with low vitamin D – July 2013

• 8X higher Osteoporosis risk if high level of vitamin A, vitamin D important too – Feb 2013

• Low Vitamin D or Vitamin K2 may be a cause of Hypertension and Osteoporosis – Nov 2012

• Overview Magnesium and vitamin D

• Overview: Omega-3 many benefits include helping vitamin D

• Overview Vitamin K and Vitamin D

• Search Vitamin D Life for "Bone Strength" 115 hits as of Sept 2013

• Belgian Bone Club file

• Healthy bones need: Calcium, Vitamin D, Magnesium, Silicon, Vitamin K, and Boron – 2012

• Vitamin K-2 (180 ug MK-7) helped both bone density and strength – RCT March 2013

• Overview Fractures and vitamin D

• Overview Fractures and Falls and Vitamin D