Coimbra high-dose vitamin D protocol - many studies
40+ Vitamin D Life pages have COIMBRA in the title
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Autoimmune Diseases and high-dose Vitamin D (Coimbra protocol) - 60 minute video Oct 2022
01:39 Experience with Coimbra protocol
02:17 Medical background; neurology
04:49 Conventional medicine is pharmacological intervention
07:18 Field of neurology is conservative
08:12 Large doses of vitamin D and calcium metabolism
11:56 Ataxia treatment
12:59 Resignation from hospital and working with autoimmune patients
14:32 Medical community reception of Comibra protocol
15:49 Vitamin D in evolution
16:45 Vitamin D and hormones
18:15 Different branches of metabolism
19:26 Plant-based vs. animal-based vitamin D
19:43 Are people with autoimmune disease vitamin D-resistant?
21:57 German scientist studying vitamin D in Finland
24:41 Greenland Eskimos and rickets
25:32 Vitamin D receptor protein
29:36 Vitamin D role in body
31:30 Blocking vitamin D receptors; Lyme disease
34:37 Vitamin K and vitamin D
37:54 Vitamin D and parathyroid hormones
40:55 Kidneys and hypercalcemia in Coimbra protocol
43:20 Adapting to problems
45:56 Vitamin D for other autoimmune diseases
46:35 Crohn's and ulcerative colitis; lupus erythematosus; psoriasis
49:04 Untreated vitamin D resistance and chance of getting an autoimmune disease
49:34 Making lifestyle changes
50:44 Carnivore diet for patients
53:28 Dangers of high dose vitamin D
55:13 Signs of vitamin D overdose
56:05 Don’t try this at home
58:01 Abnormal range serum calcium
Interview with Dr. Menendez - Coimbra Protocol and Vitamin D 66 minutes Sept 2024
(01:13) Dr. Sergio Menendez is a specialist in autoimmune diseases who studied medicine in Havana, completed his PhD in neurological science in Brazil, and has treated over 4,500 patients with the Coimbra Protocol since 2012.
(09:28) The Coimbra Protocol was created by neurologist Dr. Coimbra in 2002 and is based on high doses of vitamin D to control autoimmune diseases, with approximately 90% of patients experiencing disease remission.
(10:15) Autoimmune diseases occur when the immune system mistakenly attacks the body's own tissues, producing autoantibodies that cause inflammation and tissue damage in specific regions (examples: multiple sclerosis, rheumatoid arthritis, lupus).
(18:23) Dr. Coimbra discovered that patients with autoimmune diseases have resistance to converting inactive vitamin D to active vitamin D, requiring much higher doses than typically prescribed to receive therapeutic benefits.
(22:40) Vitamin D has three key functions in controlling autoimmune diseases: increasing defense against pathogens, improving immune tolerance, and blocking autoimmune inflammatory responses.
(24:51) The main potential toxicity concern with high-dose vitamin D is excessive calcium absorption, which can damage kidneys. Patients must follow dietary restrictions (avoiding dairy products, certain seeds) and drink plenty of water to maintain calcium balance.
(36:42) Symptoms of excessive calcium include persistent thirst, nausea, vomiting, constipation, stomach pain, and loss of appetite. If these occur, patients should stop the protocol and contact their doctor.
(42:54) The protocol requires ongoing supervision by doctors specifically trained in the Coimbra Protocol through blood and urine tests. Patients can find qualified doctors worldwide (though they are limited in France).
(45:02) Treatment duration varies, as autoimmune diseases are chronic. Some patients need high doses for many years while others can eventually reduce to maintenance doses of 10,000 IU daily .
(59:28) Beyond the protocol, patients should manage stress levels, get adequate rest, maintain physical activity, and follow a healthy lifestyle to reduce autoimmune disease risk factors.
Coimbra Protocol: Multiple Sclerosis & Tumor Diseases | Dr. Petra Wiechel July 2024 29 minutes
(00:00-00:45) Introduction to the "Coimbra Protocol," a revolutionary approach developed by Professor Coimbra, a neurologist at the University of St. Paul.
(01:27-03:12) The protocol focuses on vitamin D's role in autoimmune diseases, particularly MS. Vitamin D affects 249 gene expressions per cell and controls hundreds of thousands of immune reactions, but modern lifestyles limit our sun exposure and vitamin D production.
(04:07-05:37) Professor Coimbra discovered that increasing vitamin D dosage gradually (from 5,000 to 40,000+ units) can help MS patients by saturating cells with vitamin D, as people with autoimmune diseases have vitamin D receptor issues.
(06:59-08:22) The protocol requires medical supervision and should not be attempted by laypeople. It involves careful monitoring and personalized dosing, which has reportedly helped many MS patients regain mobility.
(09:18-10:49) Following the protocol requires dietary changes, particularly limiting calcium intake from dairy products, as vitamin D increases calcium absorption, which could potentially cause kidney issues if not monitored properly.
(12:30-14:18) The protocol has shown benefits for various autoimmune conditions beyond MS, including psoriasis, vitiligo, and other neurodegenerative diseases, with dosages reaching up to 300,000 units per day in some cases.
(16:42-19:26) Despite numerous studies on vitamin D's importance, there's a "knowledge resistance" in mainstream medicine. Many doctors don't routinely check vitamin D levels, though it was once common practice to supplement children.
(20:10-22:37) Vitamin D supplementation can have dramatic effects on other conditions like depression. Dr. Wiechel recommends measuring vitamin D levels in March and October and supplementing accordingly.
(23:26-25:41) Vitamin D acts like "police" in the body, helping natural killer cells recognize and eliminate cancer cells . Studies show 30% fewer tumors in people with adequate vitamin D levels.
(26:29-28:19) Conclusion encourages viewers to check their vitamin D levels and consider the Coimbra Protocol if dealing with MS or autoimmune conditions, emphasizing the importance of expert supervision.
The Coimbra Protocols of Vitamin D in Managing Autoimmune Diseases, What is Vitamin D Resistance? 23 minutes Jan 2025
(00:00) The Coimbra Protocol uses therapeutic doses of vitamin D to manage various autoimmune conditions including lupus, rheumatoid arthritis, IBS, psoriasis, multiple sclerosis, and type 1 diabetes.
(01:19) Autoimmune disorders involve either immunodeficiency (immune system too weak) or hypersensitivity (immune system misdirected), with 60-80 chronic inflammatory diseases affecting 5-8% of the US population, with 75% of cases occurring in women.
(03:21) Autoimmunity can affect any organ system and has been dramatically increasing since the 1950s, with environmental factors, genetic predisposition, and vitamin D deficiency as major contributing factors.
(09:52) A case study from Finland showed an inverse relationship between recommended vitamin D intake and type 1 diabetes incidence - as vitamin D recommendations decreased from 4,500 IU (1964) to 400 IU (1992), diabetes cases significantly increased.
(11:39) Vitamin D modulates immune response by promoting a shift from Th1 to Th2, suppressing inflammatory Th17 reactions, and facilitating T-regulatory cells that balance immune response.
(13:39) Vitamin D deficiency contributes to gut dysbiosis and leaky gut, which can trigger autoimmune responses; proper vitamin D supplementation helps reduce inflammation and strengthen gut barrier function.
(16:39) Research shows that doubling serum vitamin D concentration decreases multiple sclerosis exacerbation rates by 27%, with similar benefits demonstrated for psoriasis, vitiligo, rheumatoid arthritis, and lupus.
(19:54) Many autoimmune patients have "vitamin D resistance" due to genetic polymorphisms, requiring much higher therapeutic doses than typically recommended to achieve immunomodulatory effects.
(21:43) Case studies show lesions in multiple sclerosis patients completely disappearing after high-dose vitamin D therapy, with Dr. Coimbra describing vitamin D deficiency as "a disaster for the immune system."
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