Omega-3 may reduce weight gain and maintain weight loss
Omega-3 fatty acids in obesity and metabolic syndrome: a mechanistic update
The Journal of Nutritional Biochemistry, Vol 58, August 2018, Pages 1-16, https://doi.org/10.1016/j.jnutbio.2018.02.012
Kembra Albracht-Schulte a,b, Nishan Sudheera Kalupahanaa,b,d,⁎, Latha Ramalingama,b, Shu Wang a,b,
Shaikh Mizanoor Rahman a,b, Jacalyn Robert-McComb b, c, Naima Moustaid-Moussa a,b, [email protected]
a Department of Nutritional Sciences, Texas Tech University, Lubbock, TX, USA
b Obesity Research Cluster, Texas Tech University, Lubbock, TX, USA
c Department of Kinesiology, Texas Tech University, Lubbock, TX, USA
d Department of Physiology, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka
📄 Download the PDF from Vitamin D Life
Strategies to reduce obesity have become public health priorities as the prevalence of obesity has risen in the United States and around the world. While the anti-inflammatory and hypotriglyceridemic properties of long-chain omega-3 polyunsaturated fatty acids (n-3 PUFAs) are well known, their antiobesity effects and efficacy against metabolic syndrome, especially in humans, are still under debate. In animal models, evidence consistently suggests a role for n-3 PUFAs in reducing fat mass, particularly in the retroperitoneal and epididymal regions.
In humans, however, published research suggests that though n-3 PUFAs may not aid weight loss, they may attenuate further weight gain and could be useful in the diet or as a supplement to help maintain weight loss . Proposed mechanisms by which n-3 PUFAs may work to improve body composition and counteract obesity-related metabolic changes include modulating lipid metabolism; regulating adipokines, such as adiponectin and leptin; alleviating adipose tissue inflammation; promoting adipogenesis and altering epigenetic mechanisms.
Conclusions from PDF
The management of obesity has shifted from a narrow focus on BMI to the wider field that includes the complications of obesity, with the goal to reduce obesity-associated comorbidities [209]. While n-3 PUFAs have not yet shown consistent benefits in terms of weight loss in humans, improvements in the metabolic profile of obese individuals have been demonstrated.
Therefore, n-3 PUFAs may be an important adjunct to obesity management along with lifestyle modification and pharmacotherapy.
Further study of the genetic and epigenetic molecular targets related to metabolism, appetite and energetics could aid the discovery of novel therapeutic targets for obesityassociated metabolic disorders.
Vitamin D Life - studies in both categories Omega-3 and Obesity
This list is automatically updated
{category}
Overview Obesity and Vitamin D contains the following summary
{include}
Vitamin D and Omega-3 category starts with
{include}
Other Omega-3 in Vitamin D Life
Brain is helped by Omega-3 during all phases of life – Aug 2018
Omega-3 – fewer than 5 percent of adult women get the RDA – April 2018
Preterm birth rate of pregnant smokers cut in half if take Omega-3 – RCT May 2017
ICU length of stay reduced when supplement with Omega-3 – meta-analysis July 2018
Omega-3 index replaces the Omega-6 to Omega-3 ratio – March 2018
Founder of Vitamin D Life has taken Omega-3 for several decades