Severe sepsis may be prevented by 400,000 IU of vitamin D – RCT 2023

Vitamin D Status in Patients With Severe Sepsis (ViDISS)

Patients will be given 400,000 IU of vitamin D3 within 24 hours of severe sepsis onset followed by weekly doses of 25,000 IU

Principal Investigator: Sadeq A Quraishi, MD Massachusetts General Hospital

* Sepsis is both prevented and treated by Vitamin D - many studies Vitamin D Life – which includes* 200,000 and 400,000 IU of vitamin D reduced septic shock, length of stay - RCT June 2015* Two Meta-analyses of ICU and Vitamin D - April and May 2017* Sepsis injection of 300,000 IU of vitamin D helped in a small RCT Feb 2017* Sepsis is 13 X more likely if poor Vitamin D Receptor – April 2017* Sepsis: 4 fewer days in ICU if add Omega-3 – meta-analysis of 12 RCT – June 2017* See also: Vitamin D is needed before many surgeries – many studies and RCTs

Promising Vitamin D Clinical Trials - 2017 contains the following

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