Vitamin D and Human Reproduction – 51 page chapter

Created May 2017

Fahimeh Ramezani Tehrani and Samira Behboudi-Gandevani

http://dx.doi.org/10.5772/67394 251 references

* Male fertility 4 X higher if high Vitamin D – Nov 2015* Assisted Reproduction – 5 studies concluded vitamin D repletion helps – Review March 2015* Many fertility disorders associated with low vitamin D, still unsure how much is needed – Dec 2016* Pregnancy success increased 30 percent if sunny (or vitamin D) one month earlier – June 2015* Vitamin D somewhat assists reproduction – both the mother and the father – May 2014* Preterm birth 3.3 times more likely if Vitamin D Receptor gene problem – Aug 2016* In-vitro Fertilization costs at least 10,000 dollars, Vitamin D costs 5 dollars 1. Healthy pregnancies need lots of vitamin D    has the following summary{include}

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Vitamin D is one of the steroid hormones.

The precursor of vitamin D, 7-dehydrocholesterol, which is an intermediary for cholesterol pathway, is available in the skin.

Ultraviolet B (UVB) radiation makes the transformation of 7-dehydrocholesterol to provitamin D3, which automatically isomerizes to cholecalciferol (vitamin D3).

Vitamin D3 is secreted into blood circulation and carried by the vitamin D-binding protein (VDBP).

Around 80-90% of vitamin D is from sunlight-derived production in the skin.

A little amount of vitamin D is also extracted from foods and/or additional supplementation.

Vitamin D has been well known for its function in maintaining calcium and phosphorus homeostasis and promoting bone mineralization.

Accumulating evidence from animal and human studies suggests that vitamin D also modulates reproductive processes in women and men and is involved in many functions of the reproductive system.

Vitamin D receptor (VDR) and vitamin D-metabolizing enzymes are found in reproductive tissues of women and men.

This chapter presents an up-to-date review for describing the function of vitamin D in female reproduction throughout reproductive ages from menarche to menopause, during pregnancy and lactation, and some disorders affecting women and also the role of vitamin D applied to male fertility.

Tags: Fertility and sperm Pregnancy