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Child 49 percent higher risk of being overweight if hypertension during pregnancy – Sept 2017

Maternal blood pressure rise during pregnancy and offspring obesity risk at 4-7 years old: the Jiaxing Birth Cohort

Vitamin D Life

Perhaps low vitamin D during pregnancy ==> Overweight child, hypertension not required

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Pages listed in BOTH the categories Pregnancy and Hypertension (preeclampsia)


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Context: Maternal hypertensive disorders during pregnancy are suggested to have an impact on offspring obesity risk. However, little is known about the prospective association of rise in maternal blood pressure within normal range during pregnancy with offspring obesity risk. Objective: We aimed to clarify the associations of diastolic and systolic blood pressure during pregnancy among normotensive women with offspring obesity risk.

Design: Prospective cohort study.

Setting: Southeast China.

Participants: Up to 2013, 88,406 mother-child pairs with anthropometric measurements of the offspring between 4-7 years of age were included in the present analysis.

Main outcomes measured: Offspring overweight/obesity risk.

Results: Among normotensive women, second and third trimester diastolic and systolic blood pressure were positively associated with offspring overweight/obesity risk: odds ratios per 10 mmHg higher second and third trimester diastolic blood pressure were: 1.05 (95% confidence interval: 1.01, 1.09) and 1.05 (1.02, 1.10), respectively; and for systolic blood pressure: 1.08 (1.05, 1.11) and 1.06 (1.03, 1.09). Each 10 mmHg greater rise in blood pressure between first to third trimester was associated with higher risk of offspring overweight/obesity, with diastolic: 1.06 (1.01, 1.10) and systolic: 1.05 (1.02, 1.07). Among all women (combining normotensive and hypertensive women), maternal hypertension in the second and third trimester was associated with 49% and 14% higher risk of offspring overweight/obesity respectively.

Conclusions: These results suggest that rise in maternal blood pressure during pregnancy and pregnancy hypertension, independent of maternal body size prior to pregnancy, are risk factors for offspring childhood obesity. We studied the association between maternal pregnancy blood pressure and offspring obesity risk, and found that rise in pregnancy blood pressure was associated with a higher risk of offspring obesity


Created by admin. Last Modification: Thursday September 28, 2017 01:56:11 GMT-0000 by admin. (Version 3)

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8486 Hypertension in pregnancy leads to childhood obesity.pdf PDF 2017 admin 28 Sep, 2017 01:49 711.24 Kb 335
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