Many sleep problems are associated with low Vitamin D (children in this case) - Jan 2022

The Role of Vitamin D in Sleep Disorders of Children and Adolescents: A Systematic Review

J. Mol. Sci. 2022,23, 1430.https://doi.org/10.3390/ijms23031430
Federica Prono 1, Katerina Bernardi1, Raffaele Ferri 2 and Oliviero Bruni 3 0
Child Neurology and Psychiatry Unit, Department of Human Neurosciences, Sapienza University,
00185 Rome, Italy; federica.prono at uniroma1.it (F.P.); katerina.bernardi at uniroma1.it (K.B.)
Sleep Research Centre, Department of Neurology IC, Oasi Research Institute—IRCCS, 94108 Troina, Italy; rferri at oasi.en.it
Department of Developmental and Social Psychology, Sapienza University, 00185 Rome, Italy * Correspondence: oliviero.bruni at uniroma1.it; Tel.: +39-3356078964

This review investigates the association between vitamin D and sleep disorders. Vitamin D is an essential nutrient known to play an important role in the growth and bone health of the human body, but it also appears to play a role in sleep. The goal of our review is to examine the association between vitamin D and sleep disorders in children and adolescents. We summarize the evidence about the role and the mechanism of action of vitamin D in children and adolescents with sleep disorders such as insomnia, obstructive sleep apnea (OSA), restless legs syndrome (RLS), and other sleep disorders. Systematic electronic database searches were conducted using Pubmed and Cochrane Library. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline was followed. The studies that met the established inclusion criteria were analyzed and compared.
Results suggest a strict relationship between vitamin D deficiency in children and sleep disorders. There is evidence that vitamin D is implicated in the different neurochemical mechanisms involved in sleep regulation and mainly in the serotonergic and dopaminergic pathways.
This might be responsible for the association of vitamin D deficiency and

• restless sleep,
• sleep hyperhidrosis,
• OSA, and
• RLS.

 Download the PDF from Vitamin D Life

Vitamin D Life - Sleep category starts with:

A few items in SLEEP category

• Sleep greatly improved by 50,000 IU of vitamin D once every two weeks – RCT Sept 2018
• Sleeps disorders nicely treated by Vitamin D (50,000 IU twice a month) – RCT May 2017
• Sleep, Dr. Gominak and Vitamin D - several studies
• Restless Legs Syndrome dramatically reduced by vitamin D, etc
• On the job sleepiness 2.2X more likely if low vitamin D – Feb 2020
• Poor sleep 1.5 X more likely if less than 20 ng of Vitamin D – Feb 2019
• The Better Sleep Vitamin (Vitamin D) – nice 3 dollar book Feb 2015
• The worse the sleep apnea, the lower the vitamin D levels – meta-analysis 2017, 2020
• Vitamin D for better sleep video - Dec 2021
• 5X increase in sleep problems in a decade in US Veterans
• Sleep Apnea and Vitamin D - many studies
• Melatonin and Vitamin D - many studies does much more than improve sleep

Vitamin D Life - in both categories of Sleep and Children