Overview of the controversy
- A few governments say 10 ng is OK
- Some governments say 20 ng is OK
- Some governments say 30 ng is OK
- Most experts say 40 ng is good
- Some experts say 50 ng is much better for disease prevention
- A few people think that > 80 ng is needed to deal with possible vitamin D restrictions due to genes
- One doctor found that >80 ng was the right level for 2,000 patients in his clinic
- Health problems that run in families are often associated with low vitamin D
- Some experts say 50 ng is too much
- Some concern that >40 ng may be too much if taking some fixed chemotherapy or not adjust cofactors
- Some experts feel 50 ng is not enough to TREAT some diseases
- Consensus: 0 ng is bad and 30 ng is good/ok
Notional Graph of Expert Opinions of levels with Vitamin D MONOTHERAPY
Note: Monotherapy just increases vitamin D levels, and rarely adjusts the cofactor intake (Ca, Mg, Vitamin K2, Omega-3, etc)
At Vitamin D Life - need 20 - 49 ng
- Stress fractures 2X less frequent when vitamin D more than 40 ng – June 2011
- Lung cancer not reduced when vitamin D levels were less than 40 ng – June 2011
- Four reasons why vitamin D levels should be higher than 30 ng – Aug 2011
- Osteoporosis Canada Sept 2010 >30ng/ml
- Mortality reduced 30 percent when vitamin D increase by 20 ng, 35ng/ml optimal? – Dec 2011
- Traditionally living Africans have 46 ng vitamin D levels – Jan 2012
- Linus Pauling Institute >32 ng - Dec 2011
- Increasing the vitamin D level of all Canadians to 40 ng would save 6 to 18 billion dollars a year – Nov 2016
- Much less depression if more than 43 ng of vitamin D – Oct 2012
- Best heart geometry associated with vitamin D of 30-37 ng – Oct 2012
- More than 30 ng of vitamin D probably needed for long-latency diseases – Aug 2012
- Semen worse when vitamin D lower than 20 or higher than 50 ng – Oct 2012
- Teens no longer depressed after vitamin D raised to 36 ng – Feb 2012
- Hawaiians had 39 ng of vitamin D - July 2011
- Vitamin D: what clinicians need to know - Aug 2012 30-50 ng
- European Osteo group recommends 20-50 ng of vitamin D – Jan 2013
- 30 to 50 ng of vitamin D is optimal – Central Europe consensus Sept 2013
- Vitamin D supplementation guidelines (adults – 50,000 IU per week) – Feb 2017
At Vitamin D Life - 50 - 60 ng
- Saudi study defines normal Vitamin D level to be 50 to 70 ng - June 2020
- Need 51 ng to avoid premature ejaculation 2018
- Vitamin D decreases incidence of disease many charts showing great benefits 40-60 ng
- Need 30-60 ng of vitamin D for good health – Grant Jan 2011
- USANA 50 ng/ml with graph
- Dr Oz recommends 50 ng/ml vitamin D blood level May 2010
- GrassrootsHealth.net 41 experts 40-60 ng/ml after IoM report
- A group of 6,000 people have vitamin D levels higher than 50 ng – GrassrootsHealth
- Polish conference recommended vitamin D levels from 30 to 60 ng – Oct 2012
- Elite outdoor athletes had 52 ng of vitamin D – March 2013
- Populations with more than 50 ng of vitamin D
- Many more people now have vitamin D levels above 50 ng, especially seniors – May 2015
- Vitamin D is needed for human fertility – goal is 50 ng – Sept 2018
- Vitamin D - at least 4,000 IU to achieve 40-60 ng and reduce risk of early death – Holick June 2018
- Best Vitamin D- 40 to 52 ng, achieved with 4000 – 6000 IU daily – Heaney Oct 2014
- Sports benefits from up to 50 ng of Vitamin – meta-analysis - Nov 2012
- More than 30 ng of vitamin D is sometimes needed (Kidney needs 50 ng) – March 2019
At Vitamin D Life - need > 60 ng
- Pure North (Calgary) improves health by raising vitamin D to 60 ng
- Noticed bones heal faster when >60 ng of vitamin D
- Vitamin D should be 48 ng-90 ng – Heaney Sept 2011
- Need at least 80 ng of vitamin D if have chronic kidney disease – May 2012
- Many sleep disorders cured with vitamin D levels of 60 to 80 nanograms – May 2012
- Treatment (not just prevention) seems to require higher levels of vitamin D.
Example:Clinical Trial: Colon Cancer and 80-100 ng - Vitamin D level can be high, but little benefit: due to kidney, genes, low Magnesium etc.
- Dr. who got patients to vitamin D level of 80 ng - went out of business, patients became too healthy
- Autoimmune diseases such as MS treated/reversed - 150 ng of vitamin D
- Comparing High-dose vitamin D therapies 60-150 ng
At Vitamin D Life - Optimal/Treatment
- Sleep disorders cured by 60-80 ng of vitamin D and some B vitamins – March 2013
- Optimum Vitamin D level: Evidence for 30 and 40 ng – Grant Aug 2013
- Update on Treating Multiple Sclerosis with high dose vitamin D - Sept 2013 150 ng
- Need 40 to 80 ng of vitamin D to lose weight – Colgan Sept 2013
- Vitamin D of 32 to 60 ng is needed before, during, and after pregnancy – Dec 2012
- More than 30 ng of vitamin D probably needed for long-latency diseases – Aug 2012
- How often might 50000 IU vitamin D be taken - results of clinical trials
- Need at least 80 ng of vitamin D if have chronic kidney disease – May 2012
- All items in category Optimum Vitamin D
76 items At Vitamin D Life - other
- Hypothesis by Vitamin D Life – Vitamin D levels are no longer limited by evolution
- All items in category How Much Vitamin D
332 items - Consensus Vitamin D category listing has
50 items along with related searches - Overview Vitamin D Recommendations
- Same dose of vitamin D for everyone is virtually impossible - Dec 2015
- Recommendation by 25 experts most were 30-100 ng- 2010
Some indications that >40 or >50 ng may sometimes cause some problems
- Too little of cofactors such as Magnesium, Vitamin K2, etc.
- Too much of co-factor Calcium (probably just 500-750 mg]
- D interactions with some prescription drugs
- 40 ng Vitamin D perhaps optimal for reduced mortality – Meta-analysis Jan 2012
- U shaped risk curves at high latitudes that is, increasing disease risk for high levels of vitamin D
- Veith 2011 - in latitudes with high UVB fluctuation
- Dr. Grant believes this is due to long followup time - see bottom of this page
- Even if a J curve exists, it is 50X better to give vitamin D than not give it – May 2013
- Too much Vitamin D category listing has
33 items along with related searches - Perhaps increase fraility if > 40 ng see following graph
Agreement: 50 ng is NOT TOXIC
U Shaped curve due to long follow-up time, not latitude - by Dr. Grant
The U-shaped relationship comes only from prospective studies with long follow-up times.
In my considered opinion, it is an artifact of the long follow-up time, not high latitude.References (some of which are in Vitamin D Life)
- Robien K, Cutler GJ, Lazovich D. Vitamin D intake and breast cancer risk in postmenopausal women: the Iowa Women's Health Study. Cancer Causes Control. 2007 Sep;18(7):775-82.
- Lim U, Freedman DM, Hollis BW, Horst RL, Purdue MP, Chatterjee N, Weinstein SJ, Morton LM, Schatzkin A, Virtamo J, Linet MS, Hartge P, Albanes D. A prospective investigation of serum 25-hydroxyvitamin D and risk of lymphoid cancers. Int J Cancer. 2009 Feb 15;124(4):979-86.
- Grant WB. Effect of interval between serum draw and follow-up period on relative risk of cancer incidence with respect to 25-hydroxyvitamin D level; implications for meta-analyses and setting vitamin D guidelines, Dermato- Endocrinology, 2011 July, Aug Sept.;3(3) epub (lag) http://www.landesbioscience.com/journals/dermatoendocrinology/article/15364/
- Grant WB. Additional strong evidence that optimal serum 25(OH)D levels are at least 75 nmol/l. Int J Epi 2011 40: 1005-1007.
Do people with Dark Skin have a lower need for vitamin D? - Controversy
- There are some hints that some Dark Skin people need less vitamin D in the blood
- However, Traditionally living Africans have 46 ng vitamin D levels – Jan 2012
Chart of Vitamin D levels vs race - April 2013
See also PubMed
- "50 ng" "Vitamin D" 128 items as of Aug 2020
- "60 ng" "Vitamin D" 87 items as of Aug 2020
- "80 ng" "Vitamin D" 64 items as of Aug 2020
- (optimal OR optimum) "Vitamin d" 2998 items as of Aug 2020
- Note: need to also search for: 125 nmol, 150 nmol, 200 nmol
See also web - vitamin D test "reference range" = 20-100 ng
- Quest Diagnostics 20-100 ng Nov 2013, Dec 2016, March 2019
Grassroots Health infographic (2020)
short URL = http://is.gd/DlevelsIs 50 ng of vitamin D too high, just right, or not enough46317 visitors, last modified 11 Nov, 2020, This page is in the following categories (# of items in each category)Optimum76 Too much D 33 Consensus 50 Attached files
ID Name Comment Uploaded Size Downloads 14556 GRH levels 2000.jpg admin 11 Nov, 2020 16:25 106.07 Kb 7 7554 Optimal end 2016.jpg admin 23 Dec, 2016 19:23 4.39 Kb 7209 2898 Mercola Optimal.jpg admin 12 Aug, 2013 14:44 21.97 Kb 5660 See any problem with this page? Report it (FINALLY WORKS)
- Consensus Vitamin D category listing has