Those with Psoriasis were 7X more likely to have 20-30 ng levels of Vitamin D - Oct 2022

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Vitamin D status in Psoriasis: impact and clinical correlations

BMC Nutr. 2022 Oct 19;8(1):115. doi: 10.1186/s40795-022-00610-y.
Ghulam Hassan Bhat 1 2 , Sadaf Guldin # 2 , Mosin Saleem Khan # 3 4 , Mir Yasir 5 , Ganesh Prasad 1

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Psoriasis is a continuing, periodic, immune-mediated, fiery skin disease branded by hyper proliferation of epidermal keratinocytes and accompanying with inflammatory cellular infiltrate in both dermis and epidermis. Immunomodulation could be an important effect of vitamin D in Psoriasis. This case-control study was designed to measure serum 25-hydroxy vitamin D levels in patients with psoriasis and healthy controls and to find out clinical correlation, if any. Six hundred two (n = 602) subjects (285 cases and 317 controls) were taken for the study. Cases and controls were frequency matched with respect to age and gender. Various demographic and clinical details were taken using a questionnaire. Chemiluminescence Micro Particle Immunoassay was used to estimate serum 25-hydroxy vitamin D levels. The vitamin D deficiency in psoriasis patients was 60.0% vs. 17.5% in controls (P < 0.001) with mean vitamin D levels of 28.3 ± 13.9 ng/ml in psoriasis patient's vs. 37.9 ± 9.7 ng/ml in controls. Vitamin D deficiency was found to be associated with psoriasis independently of gender, age, smoking status, family history, hypertension, chronic medication, nail changes, duration of symptoms and severity of disease. Vitamin D levels were seven times lower in patients with Psoriasis as compared to controls. Reduced vitamin D levels are related to duration and clinical severity of the disease. Early detection of vitamin D deficiency and timely intervention could lead to better clinical outcome and improved quality of life in psoriasis patients.

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Vitamin D Life – Psoriasis

Some of the 70 Psoriasis articles

• Psoriasis is most strongly associated with low vitamin D (15 things were evaluated) – July 2022
• Long-term Psoriasis cured by 30,000 to 60,000 IU of Vitamin D daily (pictures and video) – early 2022
• Psoriasis paradigm shift – use topicals, like Vitamin D – Aug 2021
• Low Vitamin D plus psoriasis equals 8 times more likely to die – Dec 2020
• UV has treated psoriasis for over a century, guidelines finally agreed upon – Aug 2019
• Psoriasis severity associated with low vitamin D (10 studies) – meta-analysis Jan 2018
• Psoriasis reduced for those getting Vitamin D levels above 50 ng – RCT Feb 2018
• 35,000 IU vitamin D daily for 6 months helped ALL psoriasis suffers (106 ng) – Brazil March 2013