Ultra-low UV LED added to office desk lamp would add 7 ng to winter Vitamin D levels – RCT Oct 2022

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Ultra-low Ultraviolet Radiation in Office Lighting Can Moderate Seasonal Vitamin D Cycle: A Pilot Study

Anticancer Res . 2022 Oct;42(10):5101-5106. doi: 10.21873/anticanres.16020.
Ann R Webb 1 , Bianca M I VAN DER Zande 2 , Richard C Kift 3 , Helen O'Neil 4 , Nan Xuan Lin 5 , David Wright 4

Background/aim: Ultraviolet-B (UV-B) radiation initiates vitamin D synthesis in the skin, making sun exposure a major source of vitamin D. We aimed to determine whether office lighting containing ultra-low levels of UV-B radiation could modify the winter decline in vitamin D status in the UK, while being safe and well tolerated.

Patients and methods: Twenty commercial office desk lamps were modified with the addition of UV-B LEDs. Ten hospital office administrative staff received UV-modified lamps with UV-on, and 10 staff received identical placebo lamps with UV switched off, in a double-blind, cross-over pilot study during the winter of 2021/22. Circulating 25-hydroxyvitamin D [25(OH)D] was measured every 4 weeks for 20 weeks: at baseline and during an 8-week trial period, 4-week washout, and a cross-over 8-week trial period.

Results: The linear regression combining the complete datasets for phase 1 and 2 of the trial showed that an 8-week UV light intervention significantly increased 25OHD by 7.13 nmol/l with a p-Value=0.02, compared to the placebo group. Similar results were confirmed by cross-over analyses using the datasets of those completing both phases of the trial both with and without using the inverse probability weighing method to handle dropouts.

Conclusion: The UV-B-modified lighting was well-tolerated and safe with weekly doses of UV-B of 0.5 - 0.9 Standard Erythema Dose [SED=100 Jm-2 erythema weighted UV radiation] measured at chest level. This ultra-low dosing was effective in reducing the winter decline in vitamin D status.

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Vitamin D Life - UV and D contains

375 items in UV category   see also

• Overview UV and vitamin D
• Vitamin D bulb for use in the home - or perhaps office,
• Sun and UV
• Sun and Vitamin D category has 324 items
• UV and Vitamin D calculators,  Vitamin D from low-cost UVB lamps
• UVB added in classroom reduced cavities, increased height, increased academics. etc
• How to safely get Vitamin D at home from a UV lamp or LED
• Vitamin D production after UVB exposure – A comparison of exposed skin regions – Feb 2015
• Ultra-low UV LED added to office desk lamp would add 7 ng to winter Vitamin D levels – RCT Oct 2022
• Seniors get about 4X less vitamin D from the sun or UVB
• Vitamin D from the sun without the heat (silver-coated plexiglass)
• COVID and other Virus fought by UV - many studies 16+
• 3.3 X more likely to be Vitamin D deficient if wear long-sleeves – Oct 2022
• Non-oral Vitamin D should be a better form for MS, food allergy, PTSD, etc. – many studies UV, etc.