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Senior women having low vitamin D were 2X more likely to die - Sept 2023


Association of serum 25-hydroxyvitamin D levels with all-cause and cause-specific mortality among postmenopausal females: results from NHANES

Jia-Wei Shi, Jiang-Nan Wu, Xiao-Yong Zhu, Wen-Hui Zhou, Jin-Ying Yang & Ming-Qing Li
Journal of Translational Medicine volume 21, Article number: 629 (2023)

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Note: "Adjusted for age, race/ethnicity, education level, PIR, BMI, smoking status, alcohol intake, hypertension and diabetes". - Should not "adjust" for variables that are strongly related to low vitamin D
Background
Vitamin D deficiency is common among the population, but its relationship with mortality of postmenopausal females is unclear. The aim of this study is to explore the association between serum 25-Hydroxyvitamin D (25(OH)D) and all-cause and cause-specific mortality among postmenopausal women in the United States.

Methods
6812 participants of postmenopausal females from the National Health and Nutrition Examination Survey (2001–2018) were included in this study. The mortality status of the follow-up was ascertained by linkage to National Death Index (NDI) records through 31 December 2019. We used cox proportional hazards models to estimate the association of serum 25(OH)D concentrations and mortality of postmenopausal females.

Results
The mean level of serum 25(OH)D was 72.57 ± 29.93 nmol/L, and 65.34% had insufficient vitamin D. In postmenopausal females, low serum 25(OH)D concentrations were significantly associated with higher levels of glycohemoglobin, glucose, and lower levels of HDL. During follow-up, 1448 all-cause deaths occurred, including 393 cardiovascular disease (CVD)-related deaths and 263 cancer deaths. After multivariate adjustment, higher serum 25(OH)D levels were significantly related with lower all-cause and CVD mortality. In addition, serum 25(OH)D presented a L-shaped relationship with all-cause mortality, while appeared a U-shaped with CVD mortality, and the cut-off value is 73.89 nmol/L and 46.75 nmol/L respectively.

Conclusions
Low serum 25(OH)D levels are associated with the higher risk of all-cause and CVD mortality in postmenopausal females. These findings provide new ideas and targets for the health management of postmenopausal women.
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Vitamin D Life – Mortality contains:

People die sooner if they have low vitamin D
Mortality is.gd/VitaminDMortality
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There are 312 articles in Mortality category

Vitamin D Life - 6 Mortality of Women

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Vitamin D Life - 25 items in Mortality and Cardiovascular categories

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36+ Vitamin D Life Mortality pages have CANCER in the title

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Items found: 36
Title Modified
People with Cancer having more than 30 ng of Vitamin D are 40% less likely to die (of any cause) – Nov 2023 23 Nov, 2023
Death of women from cancer 24% less likely if 20 ng more vitamin D – meta-analysis Sept 2013 31 Jul, 2023
Cancer incidence or mortality not changed by small Vitamin D doses: 2021-2023 01 May, 2023
Prostate Cancer death 40 percent less likely if 40 ng level of vitamin D – Meta-analysis Oct 2018 30 Apr, 2023
Cancer mortality reduced 40 pcnt by 2000 IU Vitamin D daily if normal weight – Meta-analysis June 2022 03 Jul, 2022
Cancer incidence and death reduced by both Vitamin D and UVB – Grant Oct 2021 15 Oct, 2021
Cancer mortality not reduced by small vitamin D doses - Sept 2021 21 Sep, 2021
Cancer death (non-skin) 2.3 X more likely if low Vitamin D – Aug 2021 17 Aug, 2021
Deaths after Cancer Surgery higher in blacks (probably low vitamin D) – Dec 2020 10 Jan, 2021
Cancer patients in ICU with low vitamin D were 3.4 X more likely to die within a year – Dec 2020 31 Dec, 2020
Deaths from many types of Cancer associated with low vitamin D- review of meta-analyses Sept 2020 09 Nov, 2020
Cancer is leading cause of death - Vitamin D and Receptor activators help 09 Nov, 2019
Mortality increased: 4X Cancer, 5X Diabetes if eat a lot of meat protein – March 2014 08 Nov, 2019
Vitamin D Supplements Reduce Cancer Mortality – Greger Sept 2019 10 Sep, 2019
Cancer with low Vitamin D increases Mortality by 13 percent – meta-analysis Feb 2019 05 Jul, 2019
People supplemented with Vitamin D had 13 percent fewer Cancer deaths – Meta-analysis of RCT June 2019 05 Jul, 2019
Cancer incidence and mortality is decreased if 40-60 ng of Vitamin D – April 2019 07 May, 2019
Vitamin D reduced Breast Cancer mortality in 9 out of 9 studies, yet still no consensus – April 2019 13 Apr, 2019
Cancer patients 64% less likely to die if have high level of vitamin D – Dec 2011 26 Nov, 2018
Vitamin D reduces the risk of Breast Cancer, improves treatment, and improves survival 10 Sep, 2018
The “Deadly Breast Cancer Gene” Is A Myth, Lancet Study Confirms – Jan 2018 13 Jan, 2018
Lung Cancer death 60 percent less likely if high level of vitamin D – 2 meta-analysis 2017 29 Dec, 2017
Breast Cancer Mortality reduced 60 percent if more than 60 ng of Vitamin D – meta-analysis June 2017 13 Jun, 2017
Death after Breast Cancer 2 times less likely if take lots of Magnesium – Dec 2015 15 Jun, 2016
Fewer heart attacks, hip fractures and deaths if more skin cancer – Sept 2013 09 Nov, 2014
Colorectal and Breast Cancer – Vitamin D is associated with fewer deaths – meta-analysis Feb 2014 30 Sep, 2014
Cancer incidence not reduced by 1100 IU of vitamin D (proven again) but mortality decreased – June 2014 17 Jun, 2014
Cancer survival 4 percent more likely with just a little more vitamin D (4 ng) - meta-analysis July 2014 12 May, 2014
More survive Breast Cancer if more vitamin D – 2X fewer deaths with just 30 ng -meta-analysis March 2014 08 May, 2014
Death due to breast cancer reduced 40 percent if high vitamin D – meta-analysis April 2014 08 Apr, 2014
Breast Cancer survival 2X more likely if vitamin D sufficient – meta-analysis May 2013 06 Mar, 2014
Vitamin D and Cancer Mortality – review Jan 2013 17 Sep, 2013
Mortality and Cancer varies with latitude in France too – 2010 26 Oct, 2012
More US deaths due to cancer than heart if dark skinned – Sept 2012 18 Sep, 2012
Lack of solar UVB in US is associated with some Cancers - 2006 28 Dec, 2011
Solar radiation, vitamin D and cancer incidence and mortality in Norway 13 Apr, 2010


Attached files

ID Name Comment Uploaded Size Downloads
20515 Mortality charts.png admin 23 Dec, 2023 49.87 Kb 30
20514 Mortality women.png admin 23 Dec, 2023 34.67 Kb 28
20513 Postmenopausal women mortality_CompressPdf.pdf admin 23 Dec, 2023 312.99 Kb 32