Vitamin D replacement therapy in patients with cardiac syndrome X
Perfusion January 2015 vol. 30 no. 1 60-63
A Andishmand, Z Ansari, MH Soltani, H Mirshamsi mirshamsih at yahoo.com, S Raafat
Cardiovascular Research Center, Afshar Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Hamide Mirshamsi Cardiovascular Department Afshar Hospital, Jomhoori Blvd Yazd, 8917945556 Iran.
Aims: The aim of present study was to assess whether vitamin D, with proven beneficial effects on the cardiovascular system, has any effect on angina and exercise-induced ischemia in patients with cardiac syndrome X and low serum vitamin D.
Methods: Patients with cardiac syndrome X and low serum vitamin D3 were studied before and after treatment with an intramuscular injection of vitamin D3 (300,000 units, every other week for 2 months). We determined the angina episode (per day) and several indices of exercise capacity.
Results: At the end of the treatment course (75±6 day),
- a significant increase of serum vitamin D3 occurred and was within the normal range (45±8 ng/ml) and
- the frequency of angina improved significantly (p=0.003).
- Exercise duration and maximal work capacity increased significantly (p<0.001).
- Maximal ST-segment depression (mm) decreased significantly (p=0.001).
- The calculated Duck treadmill score improved significantly (p=0.001).
Conclusions: Our findings show that vitamin D replacement therapy in patients with cardiac syndrome X and vitamin D deficiency dramatically improves symptoms and signs of ischemia.
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It appears that the main benefit of injection is that the doctor get more income and does not have to worry about compliance
secondary reason for using injection - poor digestion
300,000 IU averaged over 14 days could be as well accomplished by other means
Example: 50,000 IU of vitamin D every 2nd day
See also Vitamin D Life
- Overview Cardiovascular and vitamin D
- Cardiac syndrome X patients have very low vitamin D levels – April 2016
- Search vitaminDWiki for ANGINA 108 items as of Oct 2016
- Search Vitamin D Life for INJECTION 789 items as of Oct 2016
- Review of Vitamin D (including free, frequency, injection, how much.) – Sept 2013
- Vitamin D supplementation protocols: loading, injection, etc – RCT June 2014
- Overview Pain and Vitamin D
See also web
- Effect of Vitamin D on Anginal Episodes in Vitamin D Deficient Patients with Chronic Stable Angina on Medical Management Aug 2016
60,000 IU weekly for 8 weeks ==> 20% reduction in # of episodes
 Download the PDF from Vitamin D Life