Vitamin D Intake and Magnetic Resonance Parameters for Knee Osteoarthritis: Data from the Osteoarthritis Initiative
Calcified Tissue International. Nov 2018, Vol 103, Issue 5, pp 522–528, https://doi.org/10.1007/s00223-018-0448-7
Nicola Veronese Luciana La Tegola Maria Mattera Stefania Maggi Giuseppe Guglielmi
Just 250 IU extra Vitamin D was associated with 8 better MRI readings
- Knee Osteoarthritis benefited by 20 ng of Vitamin D for 5 years – RCT July 2018
- Reduced knee osteoarthritis if consistently supplement with vitamin D for 2 years – April 2017
- Knee osteoarthritis pain reduced by 60,000 IU monthly vitamin D following loading dose – RCT Nov 2013
- Knee osteoarthritis strongly associated with low Boron – 2015
- Knee joint space narrowing (Osteoarthritis) 1.5X worse with low vitamin D – meta-analysis Sept 2015
- Knee Osteoarthritis (Radiographic ) 3X less if have lots of Magnesium – May 2015
- I needed more than Vitamin D to treat my knee osteoarthritis
- Personal note by founder of Vitamin D Life: Vitamin D + Magnesium + Boron
Osteoarthritis category includes the following
190 items in category - see also Overview Osteoporosis and vitamin D - Overview Fractures and vitamin D
- Bone - Health
269 items - Search BMD OR Bone Mineral Density 3250 results as of July 2020
- Search Vitamin D Life for OSTEOPENIA 1740 items as of July 2020
Pages in BOTH the categories Osteoporosis and Meta-analysis
- Osteoporosis Risk varies with Vitamin D Receptor – meta-analysis July 2020
- Osteoporosis 15 percent more likely if poor Vitamin D receptor – meta-analysis Dec 2018
- Fractures reduced with any amount of vitamin D and some Calcium - Cochraine April 2014
- Vitamin D Receptor genes bb and BB and Osteoporosis, esp. for blacks – meta-analysis Nov 2012
- Hip fractures reduced 30 percent with 800 IU of vitamin D – meta-analysis July 2012
- Vitamin D for elderly 800 to 2000 IU - Osteoporosis Canada - Sept 2010
- Hip fractures in India - editorial with recommendation - Sept 2010
- Cochrane review finds that Vitamin D and Calcium treat osteoporosis – Feb 2010
PDF is available free at Sci-Hub 10.1007/s00223-018-0448-7
Purpose
There is evidence that vitamin D may play a role in the osteoarthritis (OA) pathogenesis, but the few data available are limited to X-rays and clinical findings. The aim of this study was to investigate whether a higher intake of vitamin D was associated with a better architecture of the cartilage of the knee, assessed with magnetic resonance (MRI), in a large cohort from North America.Methods
783 participants (59.8% females; mean age: 62.3 years) with an MRI assessment from the Osteoarthritis Initiative were included. Vitamin D dietary intake was calculated as the sum of food and oral supplementation. A coronal 3D FLASH with Water Excitation MR sequence of the right knees was used. The strength of the association between dietary vitamin D intake and knee MRI parameters was investigated through an adjusted linear regression analysis, reported as standardized betas with 95% confidence intervals (CIs).Results
Using a linear regression analysis, adjusted for ten potential confounders, higher vitamin D intake (reported as an increase in one standard deviation, = 250 IU) corresponded to significantly higher values of- mean cartilage thickness and
- volume of cartilage at medial tibia,
- volume of cartilage and
- mean cartilage thickness at central lateral femur,
- volume of cartilage and
- mean cartilage thickness at central medial femur, and
- volume of cartilage and
- mean cartilage thickness at central medial tibial-femoral compartment.
Conclusions
Higher vitamin D intake is associated with a significantly better architecture of the cartilage of the knee, also independently taking in account from several potential confounders.Less Knee Osteoarthritis if take more Vitamin D – 8 MRI confirmations – Nov 20181181 visitors, last modified 07 Sep, 2019, This page is in the following categories (# of items in each category)