Mortality in an Italian nursing home during COVID-19 pandemic: correlation with gender, age, ADL, vitamin D supplementation, and limitations of the diagnostic tests
AGING 2020, Vol. 12, No. 24
4X less likely FOR ANY AMOUNT of Vitamin D = (17/56) / (3/42)
The amount and timing of the Vitamin D is nogt given in the study.
Suspect that the Italian dosing was less than that given in a French nursing home
- 9X COVID-19 survival in nursing home if had 80,000 IU dose of vitamin D in previous month – Oct 2020
COVID-19 treated by Vitamin D - studies, reports, videos
As of Jan 23 had: 34 trials, 4 trial results, 12 meta-analyses and reviews, 44 observations, 25 recommendations, 42 associations, 83 speculations, 37 videos see also COVID-19 and Vitamin D: Governments. Health problems. Hospitals
The study on this page was the 38th observation
Items in both categories Virus and Mortality are listed here:
- Elderly COVID-19 patients getting 400,000 IU of vitamin D had better survival (Italy, April)– Jan 14, 2021
- Iranians with COVID-19 were 2.3 X more likely to die if low vitamin D – Jan 2021
- .Iranians with COVID-19 were 2.3 X more likely to die if low vitamin D – Jan 2021
- Poor COVID-19 prognosis was 6 X more likely if low vitamin D – Jan 21, 2021
- 30 x fewer COVID-19 deaths in those getting 400,000 IU of Vitamin D - Jan 2021
- 2.8 X fewer COVID-19 nursing home deaths if add 10,000 IU Vitamin D daily for a week (small observation)- Jan 2021
- Italian nursing home COVID-19 – 4X less likely to die if taking Vitamin D– Dec 22, 2020
- 7X less likely to die of COVID-19 if taking Vitamin D loading dose – Dec 11, 2020
- COVID-19 male mortality increased 3.9 X if low vitamin D – observation Nov 25, 2020
- Hospital COVID-19 observation: 7X more likely to live if more than 20 ng of vitamin D– Nov 19, 2020
- COVID-19 lung death 4X more likely in Iran if less than 25 ng of vitamin D – Oct 30, 2020
- 9X COVID-19 survival in nursing home if had 80,000 IU dose of vitamin D in previous month – Oct 2020
- 14.7 X more likely to die of COVID-19 if less than 12 ng of Vitamin D (185 Germans) – Sept 10, 2020
- COVID ARDS deaths 2X more likely if less than 10 ng of Vitamin D – Aug 8, 2020
- COVID-19 mortality rate highest North of 35 degrees latitude (Vitamin D) – April 20, 2020
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Biagio Cangiano1,2,3’，Letizia Maria Fatti1’，Leila Danesi1, Giacomo Gazzano4, Marina Croci1, Giovanni Vitale1,3,5, Luisa Gilardini1, Stefania Bonadonna1, Iacopo Chiodini1,2, Chiara Francesca Caparello6, Antonio Conti1, Luca Persani1,2,3, Marco Stramba-Badiale7, Marco Bonomi1,2,3 m.bonomi at auxologico.it, marco.bonomi at unimi.it on behalf of the “Mons G. Bicchierai” nursing home group#
Introduction: The COVID-19 pandemic caused an increased mortality in nursing homes due to its quick spread and the age-related high lethality.
Results: We observed a two-month mortality of 40%, compared to 6.4% in the previous year. This increase was seen in both COVID-19 positive (43%) and negative (24%) residents, but 8 patients among those testing negative on the swab, tested positive on serological tests. Increased mortality was associated with male gender, older age, no previous vitamin D supplementation and worse “activities of daily living (ADL)” scores, such as Barthel index, Tinetti scale and S.OS.I.A. classification.
Conclusion: Our data confirms a higher geriatric mortality due to COVID-19. Negative residents also had higher mortality, which we suspect is secondary to preanalytical error and a low sensitivity of the swab test in poorly compliant subjects. Male gender, older age and low scores on ADL scales (probably due to immobility) are risk factors for COVID-19 related mortality. Finally, mortality was inversely associated with vitamin D supplementation.
Design: In this observational study, we described the two-month mortality among the 157 residents (age 60100) of a nursing home after Sars-CoV-2 spreading, reporting the factors associated with the outcome. We also compared the diagnostic tests for Sars-CoV-2.