The effects of three regimens of cholecalciferol (vitamin D3) supplementation on vitamin D deficiency in non-obese and obese females.
Arch Med Sci Atheroscler Dis. 2018 Mar 27;3:e60-e67. doi: 10.5114/amsad.2018.74784
Imga NN1, Berker D1, Can B1, Guler S1.
This study: Daily vs. Weekly 50,000 IU oral Vitamin D for 8 weeks
Obese lost more weight on diet if added 50,000 IU of vitamin D weekly – many RCTs
- One pill every two weeks gives you all the vitamin D most adults need
- Which includes "32 health problems fought by 50,000 Vitamin D weekly "
A sampling of the many RCT which found weekly to work well (often 50,000 IU was used)
- 50,000 IU of vitamin D weekly following cardiac failure helps – RCT 2014
- Depression in adolescent girls reduced somewhat by 50,000 IU weekly for 9 weeks – July 2017
- Irritable Bowel Syndrome treated by weekly 50,000 IU Vitamin D – RCT Feb 2019
- Peripheral diabetic neuropathy helped by weekly 50,000 IU vitamin D – Jan 2019
- Urgency Urinary Incontinence in senior black women decreased 40 percent by weekly 50,000 IU vitamin D – RCT Dec 2018
- Attention-Deficit Hyperactivity Disorder treated by weekly 50,000 IU of vitamin D – RCT Nov 2018
- Depression in seniors treated by weekly 50,000 IU of vitamin D – RCT Sept 2018
- Hashimoto's thyroiditis helped by weekly 50,000 IU of vitamin D – RCT May 2019
- Athletes helped by weekly 50,000 IU Vitamin D – RCT Aug 2019
Weekly may be BETTER than daily
- Vitamin D dosing - weekly may be better than daily – video Aug 2018
- Weekly Vitamin D to mother after birth much better than daily - RCT Aug 2018
Non weekly
- Monthly 100,000 IU of vitamin D is safe (and may be better than daily) – RCT Aug 2018
- Vitamin D update – 40-60 ng ideal, 50K biweekly maintenance – Jan 2014
- Pregnancies helped a lot by Vitamin D (injection then 50,000 IU monthly) – RCT May 2018
- 100,000 IU of vitamin D monthly decreases use of NASIDs by 13 percent if low vitamin D – RCT May 2018
- Autism treated by Vitamin D (monthly injection of 150,000 IU) – June 2017
- Less bone loss if take 100,000 IU vitamin D monthly – RCT Nov 2017
193 items in category Intervention - non daily 1 or 2 per month may be BETTER than daily
- 50,000 IU of vitamin D every two weeks – Jordan conclusion - RCT July 2017
- 50,000 every two weeks is slightly better than 100,000 once a month
- Vitamin D every 25 days may be BETTER than daily – RCT May 2018
- Monthly vitamin D dosing had higher response than 3 per month – RCT Jan 2018
Take vitamin D3 daily or weekly has the following
- Notional chart for Vitamin D supplementation for levels < 30 nanograms
- Notional chart of Vitamin D benefit vs dosing frequency for > 50 nanograms
Higher gradient (steeper slide) resulting from infrequent dosing results in more Vitamin D getting into the cells.
Note: Virtually all cells of the body can utilize/activate Vitamin D, no liver or kidney neededDownload the PDF from Vitamin D Life
Note: vitamin D levels dropped by the 6th month asthere was no dosing after the 8th weekVitamin D deficiency is a common health problem worldwide and tends to be a risk factor for all-cause mortality. We evaluated the effect of continuous low-dose oral daily and loading dose of oral weekly and loading monthly intramuscular (IM) vitamin D3 regimens on circulating levels of total 25(OH)D and in vitamin D deficient females, and between non-obese and obese subgroups.
MATERIAL AND METHODS:
A total of 231 vitamin D deficient females were included to the study. According to treatment regimen, patients were divided into three groups:- daily continuous oral,
- loading dose of weekly oral
- and monthly intramuscular.
All patients in treatment groups were divided into non-obese (105) and obese (126) groups. Serum 25(OH)D and parathormone (PTH) levels were evaluated at baseline and at the third and sixth month.
RESULTS:
In obese patients oral weekly loading regimen and in non-obese patients oral daily continuous regimens were found to be more potent. Baseline PTH levels decreased when compared with the third and sixth months (p < 0.001), but between the third and sixth months it was not changed (p = 0.783).CONCLUSIONS:
- Oral daily regimen in non-obese patients and
- loading weekly oral regimen in obese patients
were more effective in achieving the target levels of 25(OH)D concentration above 30 ng/ml and provided a stable plasma vitamin D concentration over a long period of time.
Title was revised August 2019 causing the visitor count to reset.
There have actually been1448 visitors to this page since it was originally made Obese responded to weekly vitamin D better than non-obese – RCT March 2018Printer Friendly PDF this page! Follow this page for updates972 visitors, last modified 25 Dec, 2019, This page is in the following categories (# of items in each category)Obesity352 Intervention 639 Top news 815 Intervention - non daily 193 Attached files
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